Steven L. Wagner,William C. Mobley,Rudolph E. Tanzi,Graham Johnson,Ronald Buckle,Nicholas Mayhew,Robert Jason Herr,Kevin D. Rynearson
申请号：
US15522969
公开号：
US20180093967A1
申请日:
2015.10.30
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Provided herein are compounds and methods for treating a disorder associated with aberrant A3 peptide levels, including Alzheimers disease. Provided herein are compositions and methods for treating a disorder associated with aberrant Aβ peptide levels, including AD. Provided herein are compounds of Formula (A) or a pharmaceutically acceptable salt thereof, wherein, L′ is selected from the group consisting of C(O), C(R1)(R2), substituted or unsubstituted —C2-6 alkylene-, and substituted or unsubstituted —C3-6 cycloalkylene.
