Genetic polymorphisms associated with statin response and cardiovascular disease, detection methods and uses thereof

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专利权人:

セレラ コーポレーション

发明人:

シッフマン， ダフ,デブリン， ジェイムス ジェイ．,ルーク， メイ,ロス， デイビッド,シッフマン, ダフ,デブリン, ジェイムス ジェイ.,ルーク, メイ,ロス, デイビッド

申请号：

JP2013506194

公开号：

JP5918216B2

申请日:

2011.04.15

申请国别(地区):

JP

年份:

2016

代理人:

摘要：

The invention provides a method for predicting statin responsiveness in a human, the method comprising testing a sample of nucleic acid from said human for the presence or absence of a single nucleotide polymorphism (SNP) in the nucleotide sequence of SEQ ID NO:903 (rs3732788), wherein said human is determined to have an increased statin responsiveness due to the presence of C at position 101 of SEQ ID NO:903 or the presence of G at position 101 of its complement. Further provided are uses of a detection reagent and a kit for predicting said statin responsiveness.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/