Genetic polymorphisms associated with statin response and cardiovascular disease, detection methods and uses thereof

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专利权人:

セレラ コーポレーション

发明人:

ダフ シッフマン,ジェイムス ジェイ． デブリン,メイ ルーク,デイビッド ロス,ジェイムス ジェイ. デブリン

申请号：

JP2015230300

公开号：

JP6157571B2

申请日:

2015.11.26

申请国别(地区):

JP

年份:

2017

代理人:

摘要：

The invention provides a method for predicting statin responsiveness in a human, the method comprising testing a sample of nucleic acid from said human for the presence or absence of a single nucleotide polymorphism (SNP) in the nucleotide sequence of SEQ ID NO:903 (rs3732788), wherein said human is determined to have an increased statin responsiveness due to the presence of C at position 101 of SEQ ID NO:903 or the presence of G at position 101 of its complement. Further provided are uses of a detection reagent and a kit for predicting said statin responsiveness.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/