BARE, LANCE,DEVLIN, JAMES, J.,ROSENDAAL, FRITS R.,REITSMA, PIETER H.,BEZEMER, IRENE D.
申请号:
EP11838747
公开号:
EP2635709A4
申请日:
2011.11.02
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The present invention provides compositions and methods based on genetic polymorphisms that are associated with response to statin treatment (particularly for reducing the risk of venous thrombosis). For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and variant proteins, and methods of using the nucleic acid molecules and proteins as well as methods of using reagents for their detection.