Lance BARE,James J. DEVLIN,Frits R. ROSENDAAL,Pieter H. REITSMA,Irene D. BEZEMER
申请号:
US13286934
公开号:
US20120108651A1
申请日:
2011.11.01
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides compositions and methods based on genetic polymorphisms that are associated with response to statin treatment (particularly for reducing the risk of venous thrombosis). For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and variant proteins, and methods of using the nucleic acid molecules and proteins as well as methods of using reagents for their detection.