Leiden University Medical Center (LUMC) Acting on Behalf of Academic Hospital Leiden (AZL);Celera Corporation
发明人:
Lance BARE,James J. DEVLIN,Frits R. ROSENDAAL,Pieter H. REITSMA,Irene D. BEZEMER
申请号：
US14971503
公开号：
US20160244837A1
申请日:
2015.12.16
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention provides compositions and methods based on genetic polymorphisms that are associated with response to statin treatment (particularly for reducing the risk of venous thrombosis). For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and variant proteins, and methods of using the nucleic acid molecules and proteins as well as methods of using reagents for their detection.
