PROBLEM TO BE SOLVED: To provide a medical manipulator capable of preventing or suppressing the opening degree change of an end effector in the tilting operation of a leading end operation part.SOLUTION: A medical manipulator includes an on-off drive transmission part 80 for transmitting drive force from a handle to a leading end operation part. A flexible pull wire 70 constituting a part of the on-off drive transmission part 80 passes through a joint part 17 to extend into the leading end operation part. A guide part 82 for guiding the on-off drive transmission part 80 is provided on both sides of the tilting direction of the leading end operation part of the on-off drive transmission part 80 (pull wire 70) in the vicinity of the tilting fulcrum to a shaft 18 of the leading end operation part.
