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ANALOGS OF 3-AMINO-4-(PROPAN-2-YLIDENE)CYCLOPENTANE-1-CARBOXYLIC ACID AND USES THEREOF FOR TREATING DISEASES AND DISORDERS ASSOCIATED WITH ORNITHINE AMINOTRANSFERASE ACTIVITY
专利权人:
Northwestern University
发明人:
Richard B. Silverman,Matthew J. Moschitto
申请号:
US16800753
公开号:
US20200299296A1
申请日:
2020.02.25
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed are compound and methods of using the compounds for modulating ornithine aminotransferase (OAT) activity. The disclosed compound are characterized as analogs of 3-amino-4-(propan-2-ylidene)cyclopentane-1-carboxylic acid which may be formulated as therapeutic agents for treating diseases and disorders associated with ornithine aminotransferase (OAT) activity such as hepatocellular carcinoma and other cancers.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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