The invention relates to an affinity chromatography matrix, in the form of a gel, comprising polymer particles onto which at least one oligosaccharide corresponding to a blood group A and/or blood group B epitope is grafted, via a spacer, characterized in that the oligosaccharide density is between 0.2 and 0.7 mg/ml of matrix. The invention also relates to the uses of this matrix for preparing immunoglobulin concentrates for therapeutic use.本發明係關於一種呈凝膠形式之親和層析基質，其組成包括聚合物粒子；在此等粒子中，至少需要移植一個與A型血基團及/或B型血基團抗原決定基相對應之寡醣；該寡醣經由間隔基移植至該等粒子內；其特徵在於寡醣中所含基質之密度為0.2至0.7mg/ml。本發明亦關於將該基質用於製備具有治療用途之免疫球蛋白濃縮物。
