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NOVEL PHARMACEUTICAL PROCESS FOR CHEWABLE FORMULATION
专利权人:
发明人:
MANOJ KUMAR SINGH
申请号:
IN3436/CHE/2013
公开号:
IN2013CH03436A
申请日:
2013.07.31
申请国别(地区):
IN
年份:
2014
代理人:
摘要:
ABSTRACT The invention pertains to a reasonable process of developing an excipient base comprising a soft chewable hematinic tablet comprising coating with Methacrylic acid and Methacrylate copolymers for gastro-resistant activity and effective taste masking activity, providing overall target release into the duodenum. The copolymer coating done by multi-layer particle (granule) coating technology by fluid bed processor. The excipient base also provides combination of mouth-feel enhancing diluents along with an acidifier, alkalizer, sweetener and flavors for providing improved taste, stabilization and mouth-feel qualities, followed by seal coating for moisture barrier, and a film coat comprising the same sweetener, flavor and colorants as used in wet granulation and pre-lubrication.
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