Ivan Alferiev,Ilia Fishbein,Michael Chorny,Robert J. Levy,Benjamin Yellen,Darryl Williams
申请号：
US12633593
公开号：
US08263127B2
申请日:
2009.12.08
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A water-soluble photo-activatable polymer including: a photo-activatable group adapted to be activated by an irradiation source and to form a covalent bond between the water-soluble photo-activatable polymer and a matrix having at least one carbon a reactive group adapted to covalently react with a biomaterial for subsequent delivery of the biomaterial to a cell a hydrophilic group and a polymer precursor. A composition including a monomolecular layer of the water-soluble photo-activatable polymer and a matrix having at least one carbon, wherein the monomolecular layer is covalently attached to the matrix by a covalent bond between the photo-activatable group and the at least one carbon. The composition further includes a biomaterial having a plurality of active groups, wherein the biomaterial is covalently attached to the monomolecular layer by covalent bonding between the active groups and reactive groups. Also provided is a method for delivery of a biomaterial to a cell.
