Bong Ho Lee,Seongho Kim,Hyeon-Cheol Shin,Haengwo Lee
申请号:
US14817215
公开号:
US20150335614A1
申请日:
2015.08.04
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Disclosed are a composition for reducing beta amyloid-induced neurotoxicity by inhibiting β-secretase activity, comprising a dibenzofuran derivative, and a method for preparing the same. Further disclosed is that the combination of the dibenzofuran derivative with a γ-secretase inhibitor or an anti-inflammatory agent shows higher activity with respect to reducing beta amyloid-induced neurotoxicity.