Bong-Ho LEE,Seongho KIM,Hyeon-Cheol SHIN,Haengwoo LEE
申请号:
US13796025
公开号:
US20130196976A1
申请日:
2013.03.12
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Disclosed are a composition for reducing beta amyloid-induced neurotoxicity by inhibiting β-secretase activity, comprising a dibenzofuran derivative, and a method for preparing the same. Further disclosed is that the combination of the dibenzofuran derivative with a γ-secretase inhibitor or an anti-inflammatory agent shows higher activity with respect to reducing beta amyloid-induced neurotoxicity.