Hyeon-Cheol SHIN;Haengwoo LEE;Bong-Ho LEE;Seongho KIM
发明人:
Bong-Ho LEE,Seongho KIM,Hyeon-Cheol SHIN,Haengwoo LEE
申请号：
US12948054
公开号：
US20120122822A1
申请日:
2010.11.17
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed are a composition for reducing beta amyloid-induced neurotoxicity by inhibiting β-secretase activity, comprising a dibenzofuran derivative, and a method for preparing the same. Further disclosed is that the combination of the dibenzofuran derivative with a γ-secretase inhibitor or an anti-inflammatory agent shows higher activity with respect to reducing beta amyloid-induced neurotoxicity.
