MADEC FREDERIC,LECANE PHIL,MARKS PHILLIP,FOSTER KEITH
申请号:
ZA201008425
公开号:
ZA201008425B
申请日:
2010.11.24
申请国别(地区):
ZA
年份:
2012
代理人:
摘要:
The present invention relates to a method for suppressing or treating cancer, in particular to a method for suppressing or treating one or more of colorectal cancer, breast cancer, prostate cancer and/ or lung cancer. The therapy employs use of a non-cytotoxic protease, which is targeted to a growth hormone-secreting cell such as to a pituitary cell. When so delivered, the protease is internalised and inhibits secretion/ transmission of growth hormone from said cell. The present invention also relates to polypeptides and nucleic acids for use in said methods.