Madec, Frederic,Lecane, Phil,Marks, Philip,Foster, Keith
申请号:
AU2011203062
公开号:
AU2011203062A1
申请日:
2011.06.23
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
#$%^&*AU2011203062A120130117.pdf#####ABSTRACT Suppression of cancer 5 The present invention relates to a method for suppressing or treating cancer, in particular to a method for suppressing or treating one or more of colorectal cancer, breast cancer, prostate cancer and/ or lung cancer. The therapy employs use of a non-cytotoxic protease, which is targeted to a growth hormone-secreting cell such as to a pituitary cell. When so 10 delivered, the protease is internalised and inhibits secretion/ transmission of growth hormone from said cell. The present invention also relates to polypeptides and nucleic acids for use in said methods. 15 20 25 30 144