Marks, Philip,Madec, Frederic,Lecane, Phil,Foster, Keith
申请号:
AU2009259034
公开号:
AU2009259034B2
申请日:
2009.06.11
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present invention relates to a method for suppressing or treating cancer, in particular to a method for suppressing or treating one or more of colorectal cancer, breast cancer, prostate cancer and/ or lung cancer. The therapy employs use of anon-cytotoxic protease, which is targeted to a growth hormone-secreting cell such as to a pituitary cell.When so delivered, the protease is internalised and inhibits secretion/ transmission of growth hormonefromsaid cell. The present invention also relates to polypeptides and nucleic acids for use in said methods.