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Piperazine derivatives for the treatment of urinary incontinence and pain
专利权人:
ASTELLAS PHARMA INC.
发明人:
ISHII TAKAHIRO,ISHII Takahiro,SUGANE TAKASHI,SUGANE Takashi,MAEDA JUN,MAEDA Jun,NARAZAKI FUMIE,NARAZAKI Fumie,KAKEFUDA AKIO,KAKEFUDA Akio,SATO KENTARO,SATO Kentaro,TAKAHASHI TATSUHISA,TAKAHASHI Tatsuh
申请号:
SI200631681
公开号:
SI1849773T1
申请日:
2006.02.16
申请国别(地区):
SI
年份:
2013
代理人:
摘要:
[Problem] To provide a compound usable for treatment of diseases associated with fatty acid amide hydrolase (FAAH), especially for treatment of urinary frequency and urinary incontinence, overactive bladder and/or pain. [Means for Solution] We have found that a novel pyridyl non-aromatic nitrogen-containing heterocyclic-1-carboxylate derivative and its pharmaceutically acceptable salt has a potent FAAH-inhibitory activity. Further, the pyridyl non-aromatic nitrogen-containing heterocyclic-1-carboxylate derivative of the present invention has an excellent effect for increasing an effective bladder capacity, an excellent effect for relieving urinary frequency and an excellent anti-allodynia effect, and is therefore usable for treatment of urinary frequency and urinary incontinence, overactive bladder and/or pain.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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