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Pochodne piperazyny do leczenia nietrzymania moczu i bólu
专利权人:
Astellas Pharma Inc.
发明人:
ISHII, TAKAHIRO,SUGANE, TAKASHI,MAEDA, JUN,NARAZAKI, FUMIE,KAKEFUDA, AKIO,SATO, KENTARO,TAKAHASHI, TATSUHISA,KANAYAMA, TAKATOSHI,SAITOH, CHIKASHI,SUZUKI, JOTARO,KANAI, CHISATO
申请号:
PL06713839
公开号:
PL1849773T3
申请日:
2006.02.16
申请国别(地区):
PL
年份:
2014
代理人:
摘要:
[Problem] To provide a compound usable for treatment of diseases associated with fatty acid amide hydrolase (FAAH), especially for treatment of urinary frequency and urinary incontinence, overactive bladder and/or pain. [Means for Solution] We have found that a novel pyridyl non-aromatic nitrogen-containing heterocyclic-1-carboxylate derivative and its pharmaceutically acceptable salt has a potent FAAH-inhibitory activity. Further, the pyridyl non-aromatic nitrogen-containing heterocyclic-1-carboxylate derivative of the present invention has an excellent effect for increasing an effective bladder capacity, an excellent effect for relieving urinary frequency and an excellent anti-allodynia effect, and is therefore usable for treatment of urinary frequency and urinary incontinence, overactive bladder and/or pain.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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