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תולדות של הטרוציקלים–1–קרביקסילאט המכילים פירידיל עם חנקן לא ארומטי , תכשירי רוקחות המכילים אותן והשימוש שלהן להכנת מעכב faah
专利权人:
ASTELLAS PHARMA INC.
发明人:
申请号:
IL18499807
公开号:
IL184998A
申请日:
2007.08.02
申请国别(地区):
IL
年份:
2014
代理人:
摘要:
[Problem] To provide a compound usable for treatment of diseases associated with fatty acid amide hydrolase (FAAH), especially for treatment of urinary frequency and urinary incontinence, overactive bladder and/or pain. [Means for Solution] We have found that a novel pyridyl non-aromatic nitrogen-containing heterocyclic-1-carboxylate derivative and its pharmaceutically acceptable salt has a potent FAAH-inhibitory activity. Further, the pyridyl non-aromatic nitrogen-containing heterocyclic-1-carboxylate derivative of the present invention has an excellent effect for increasing an effective bladder capacity, an excellent effect for relieving urinary frequency and an excellent anti-allodynia effect, and is therefore usable for treatment of urinary frequency and urinary incontinence, overactive bladder and/or pain.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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