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INHIBITEURS DE METALLOPROTEASES MATRICES A BASE D'HYDROXAMATES CYCLIQUES SUBSTITUES
专利权人:
INCYTE CORPORATION
发明人:
LI, YUN-LONG,ZHOU, JINCONG,BURNS, DAVID,YAO, WENQING,JALLURI, RAVI KUMAR
申请号:
CA2541509
公开号:
CA2541509C
申请日:
2004.10.15
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention provides compounds of the formula I: its enantiomers,diastereomers, racemic mixtures thereof, prodrugs, crystalline forms, non-crystalline forms, amorphous forms thereof, solvates thereof, metabolitesthereof, and pharmaceutically acceptable salts, wherein the ring A substituentgroups are fully defined in the following disclosure. The compounds of formulaI are inhibitors of metalloproteases such as matrix metalloproteases andsheddases, and are useful in treating diseases such as rheumatoid arthritis,psoriasis, neoplastic diseases, allergies and all those diseases whereininhibition of MMPs is desirable.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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