Yun-Long Li,Jincong Zhuo,David M. Burns,Wenqing Yao,Ravi Kumar Jalluri
申请号：
US14506333
公开号：
US09440958B2
申请日:
2014.10.03
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention provides compounds of the formula I:its enantiomers, diastereomers, racemic mixtures thereof, prodrugs, crystalline forms, non-crystalline forms, amorphous forms thereof, solvates thereof, metabolites thereof, and pharmaceutically acceptable salts, wherein the ring A substituent groups are fully defined in the following disclosure. The compounds of formula I are inhibitors of metalloproteases such as matrix metalloproteases and sheddases, and are useful in treating diseases such as rheumatoid arthritis, psoriasis, neoplastic diseases, allergies and all those diseases wherein inhibition of MMPs is desirable.
