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作為基質金屬蛋白酶(MMPS)抑製劑的取代環氧肟酸
专利权人:
发明人:
申请号:
HK11106411.5
公开号:
HK1152305A
申请日:
2011.06.22
申请国别(地区):
HK
年份:
2012
代理人:
摘要:
The present invention provides compounds of the formula I: its enantiomers, diastereomers, racemic mixtures thereof, prodrugs, crystalline forms, non-crystalline forms, amorphous forms thereof, solvates thereof, metabolites thereof, and pharmaceutically acceptable salts, wherein the ring A substituent groups are fully defined in the following disclosure. The compounds of formula I are inhibitors of metalloproteases such as matrix metalloproteases and sheddases, and are useful in treating diseases such as rheumatoid arthritis, psoriasis, neoplastic diseases, allergies and all those diseases wherein inhibition of MMPs is desirable.
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中国工程科技知识中心
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