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グルタミン酸塩含有液剤
专利权人:
大日本住友製薬株式会社
发明人:
竹村 等,倉本 正嗣
申请号:
JP1999240658
公开号:
JP4959864B2
申请日:
1999.08.27
申请国别(地区):
JP
年份:
2012
代理人:
摘要:
PROBLEM TO BE SOLVED: To obtain a liquid preparation composition for oral use to be an excellent liquid preparation having enhanced suppressing effects on a bitter taste without leaving an unpleasant taste in the oral cavity even after oral administration by including a bitter taste ingredient, a sugar alcohol, a sour agent and a glutamic salt.SOLUTION: This liquid preparation composition is obtained by including (A) a bitter taste ingredient (preferably quinine sulfate, morphine hydrochloride or a drug having a bitter taste similar to that thereof), (B) a sugar alcohol, (C) a sour agent, (D) a glutamic salt (preferably sodium glutamate) and preferably further (E) a stabilizer, (F) a preservative and (G) a pH adjustor. The amounts of the ingredients in the composition are preferably 0.1-0.3 wt.% of the morphine hydrochloride as the ingredient A, 20-35 wt.% of the ingredient B, 0.08-0.20 wt.% of the ingredient C and 0.1-0.5 wt.% of the ingredient D. The pH of the composition is preferably 2.0-3.0. The composition preferably contains 0.005-0.015 wt.% of the ingredient E and 0.03-0.06 wt.% of the ingredient F.COPYRIGHT: (C)2000,JPO【課題】 苦味が効果的に抑制されることにより服用が容易で、かつ服用後も口腔内に不快な味が残らない液剤の提供。【解決手段】 (a) 苦味成分、(b) 糖アルコール、(c) 酸味料及び(d) グルタミン酸塩を含有する経口用液剤組成物。
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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