A method of determining a responsiveness of a patient having brain state changes, comprising receiving an indication of a triggering event administering to the patient, in response to the indication, a test of responsiveness determining, based upon a result of the test, at least one responsiveness parameter selected from the group consisting of (i) a time of occurrence of a change in the patients responsiveness, (ii) a duration of a change in the patients responsiveness (iii) a magnitude of a change in the patients responsiveness, (iv) a time interval from the indication of event occurrence to a change in the patients responsiveness, (v) a type of change in the patients responsiveness, (vi) an estimation of a seizure severity (vii) a classification of a seizure into clinical or subclinical (viii) a classification of a clinical seizure into simple partial, complex partial, or generalized (ix) an assessment of efficacy of a therapy for the patients medical condition (x) an assessment of the state of the disease and formulation of a prognosis for the patient (xi) an estimation of a risk of injury or death for the patient and (xii) two or more thereof A medical device system capable of implementing the method.トリガ事象の兆候を受信するステップと、兆候に応答して応答性検査を患者に投与するステップと、検査の結果に基づき(i)患者の応答性変化の発生時刻、(ii)患者の応答性変化の持続時間、(iii)患者の応答性変化の大きさ、(iv)事象発生の兆候から患者の応答性変化までの時間間隔、(v)患者の応答性変化のタイプ、(vi)発作の重症度推定、(vii)発作が臨床的又は不顕性のいずれであるかの分類、(viii)臨床的発作が単純部分、複雑部分又は全身のいずれであるかの分類、(ix)患者の病状に関する治療の有効性評価、(x)病気の状態の評価及び患者の予後診断の策定、(xi)患者の傷害又は死亡の危険性の推定、及び(xii)これらの2つ以上、からなる群から選択した少なくとも1つの応答性パラメータを判定するステップを含む、脳の状態に変化がある患者の応答性を判定する方法。この方法を実装可能な医療装置システム。
