The invention is an improved structure of the medicine box of the medicine packaging machine.The utility model comprises a medicine box body and a base for containing medicine.The utility model is characterized in that the bottom space of the medicine box body protrudes the first convex axis and the second convex axis.And the first convex shaft and the second convex shaft system are respectively provided with a first transmission part and a second transmission part.And the first driving member is meshed with the second driving member.And a driving motor with a rotating shaft is arranged in the holding space of the base.And the shaft system is provided with a third transmission part.When the medicine box body is arranged above the base and combined with the base,The second driving part is meshed with the third driving part.So as to facilitate the installation or removal of the medicine box body from the base.本創作為一種包藥機藥盒之改良結構,係包括一用以盛裝藥品之藥盒本體及一底座,其特徵在於:該藥盒本體之底部空間突出第一凸軸與第二凸軸,且該第一凸軸及該第二凸軸係分別設有第一傳動件及第二傳動件,而該第一傳動件與該第二傳動件相囓合,並於該底座之容置空間內設有一具有一轉軸之驅動馬達,而該轉軸係設有第三傳動件,當該藥盒本體設置於該底座上方與該底座結合時,係令該第二傳動件與該第三傳動件相囓合,藉以達到便於人員將該藥盒本體安裝或拔除於該底座之效果。