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Selective glycosidase inhibitors, methods of making inhibitors, and uses thereof
专利权人:
Simon Fraser University
发明人:
Stubbs, Keith,Vocadlo, David,MacAuley, Matthew,Whitworth, Garrett
申请号:
AU2013200241
公开号:
AU2013200241A1
申请日:
2013.01.17
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
#$%^&*AU2013200241A120130131.pdf#####SELECTIVE GLYCOSIDASE INHIBITORS, METHODS OF MAKING INHIBITORS, AND USES THEREOF Abstract The invention comprises compounds for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions containing the compounds or prodrugs of the compounds. The invention also comprises animal models and methods of making the animal models for studying diseases and disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-GIcNAc, and treatment of such diseases and disorders. The invention also comprises methods of treating such diseases and disorders. The invention also comprises methods of making the compounds, and methods of making selective glycosidase inhibitors.
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中国工程科技知识中心
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