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Selective glycosidase inhibitors, methods of making inhibitors, and uses thereof
专利权人:
Simon Fraser University
发明人:
Vocadlo, David,MacAuley, Matthew,Whitworth, Garrett,Stubbs, Keith
申请号:
AU2006220187
公开号:
AU2006220187B2
申请日:
2006.03.01
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The invention comprises compounds for selectively inhibiting glycosidases,prodrugs of the compounds, and pharmaceutical compositions containing thecompounds or prodrugs of the compounds. The invention also comprises animalmodels and methods of making the animal models for studying diseases and disordersrelated to deficiency or overexpression of O-GIcNAcase, accumulation or deficiencyof O-GIcNAc, and treatment of such diseases and disorders. The invention alsocomprises methods of treating such diseases and disorders. The invention alsocomprises methods of making the compounds, and methods of making selective glycosidaseinhibitors.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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