Chih-Kuang Chen,Jing-Yi Lee,Wei-Shu Lu,Carl Oscar Brown, III
申请号:
US15238950
公开号:
US10195170B2
申请日:
2016.17.08
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Methods and compositions for inhibiting expression of ASC, expression of NLRP3, and/or formation of NLRP3 inflammasome complex by using diacerein or its analogs are provided. Also provided are methods and compositions for the treatment and/or prevention of a disorder mediated by ASC and/or NLRP3, and/or by formation of NLRP3 inflammasome complex by using diacerein or its analogs.