The Board of Trustees of the Leland Stanford Junior University
发明人:
Wong, Albert J.
申请号:
AU2013296164
公开号:
AU2013296164A1
申请日:
2013.08.02
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
Peptides and vaccine compositions comprising peptides based upon EGFRvIII and lacking a glycine at the splice junction are disclosed. The vaccines can induce immune responses against EGFRvIII. Methods of inhibiting formation or growth of EGFvIII tumors, methods of inducing regression of EGFvIII tumors, methods of immunizing against EGFvIII tumors and methods of treating a subjects who have EGFvIII tumors are disclosed.