The Board of Trustees of the Leland Stanford Junior University
发明人:
Albert J. Wong
申请号:
US14417752
公开号:
US09694060B2
申请日:
2013.08.02
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Peptides and vaccine compositions comprising peptides based upon EGFRvIII and lacking a glycine at the splice junction are disclosed. The vaccines can induce immune responses against EGFRvIII. Methods of inhibiting formation or growth of EGFvIII tumors, methods of inducing regression of EGFvIII tumors, methods of immunizing against EGFvIII tumors and methods of treating a subjects who have EGFvIII tumors are disclosed.