A mobile device based multi-analyte testing analyzer for use in medical diagnostic monitoring and screening, and a method of manufacturing the same are disclosed. A reflectance based, colorimetric test strip reader for use with a mobile device having a jack plug receiving socket, said test strip reader adapted for removably receiving a test strip having a test strip longitudinal axis, comprising a housing； a jack plug operably coupled to and extending from said housing and adapted for operable coupling with said jack plug receiving socket； a test strip adapter including structure defining a test strip receiving channel； a light source oriented within said housing for directing light toward said test strip receiving channel to illuminate a test strip arranged within said test strip adapter； and a light sensor oriented within said housing to sense light reflected from a test strip carried by said test strip receiving channel.
