Daniel F. Milano,Michael R. Reardon,Richard A. Silva,Benjamin M. Hutchins,Robert W. Herbst
申请号：
US16245890
公开号：
US20190270769A1
申请日:
2019.01.11
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Methods of producing, purifying, and formulating antibody drug conjugates (ADCs) are provided herein. The methods use continuous conjugation processes, single-pass tangential flow filtration, countercurrent diafiltration, and/or in-line process automation technologies. The methods decrease process times and costs and improve product consistency.
