MILANO, Daniel F.,REARDON, Michael R.,SILVA, Richard A.,HUTCHINS, Benjamin M.,HERBST, Robert W.
申请号:
SG11202005541Q
公开号:
SG11202005541QA
申请日:
2019.01.11
申请国别(地区):
SG
年份:
2020
代理人:
摘要:
Methods of producing, purifying, and formulating antibody drug conjugates (ADCs) are provided herein. The methods use continuous conjugation processes, single-pass tangential flow filtration, countercurrent diafiltration, and/or in-line process automation technologies. The methods decrease process times and costs and improve product consistency.