Niall Morrison Barr Martin,Graeme Cameron Smith,Stephen Philip Jackson,Vincent Junior M Loh,Xiao-Ling Fan Cockcroft,Ian Timothy Williams Matthews,Keith Allan Menear,Frank Kerrigan,Alan Ashworth
申请号：
US14853360
公开号：
US09566276B2
申请日:
2015.09.14
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Compounds of the formula (I):wherein A and B together represent an optionally substituted, fused aromatic ring X can be NRX or CRXRY if X═NRX then n is 1 or 2 and if X═CRXRY then n is 1 RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups RY is selected from H, hydroxy, amino or RX and RY may together form a spiro-C3-7 cycloalkyl or heterocyclyl group RC1and RC2 are both hydrogen, or when X is CRXRY, RC1, RC2, RX and RY, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring and R1 is selected from H and halo.
