The invention relates to a high-speed breakage-proof anti-pollution refrigeration centrifuge used for extracting cells. The high-speed breakage-proof anti-pollution refrigeration centrifuge comprises a box, a center console, a refrigeration mechanism, a separation mechanism, a pair of pushing wheels, and a breakage-proof recovery device, wherein the center console is arranged in an inner cavity of the box, the refrigeration mechanism and the separation mechanism are arranged in the box, and the pair of pushing wheels and the breakage-proof recovery device are arranged at the bottom of the box. An annular working groove used for mounting the separation mechanism is formed in the upper side wall of the box, and an air dissipation port and a touch control panel are arranged on the two sides of the box correspondingly. The separation mechanism comprises a centrifugal rotor arranged in the annular working groove and a rotating motor used for driving the centrifugal rotor to rotate. The high-speed breakage-proof an