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Pellet containing the herbal extract Ex having improved madescent and preparation method thereof
专利权人:
发明人:
우문제,윤병구,정재혁,홍남두,박찬성,최성원
申请号:
KR1020120075593
公开号:
KR1014194620000B1
申请日:
2012.07.11
申请国别(地区):
KR
年份:
2014
代理人:
摘要:
The present invention relates to a spherical main drug seed containing a herbal extract, a pellet formulation which increases the content of main drug based on the total weight thereof by using the spherical main drug seed, improves hygroscopicity, and contains a herbal extract, and a method for preparing the pellet formulation. The herbal extract pellet formulation prepared according to the present invention uses the main drug seed containing the herbal extract, to thereby have an effect in increasing the content of main drug based on the total weight of the pellet formulation. Therefore, when a patient takes the pellet formulation, the single dosage can be decreased so that the patient can easily take the pellet formulation. Further, when the main drug seed is prepared, the main drug seed has a sphere through particle collision due to high-rate rotation, thereby minimizing the surface area of the herbal extract, which is exposed to moisture, and thus decreasing the hygroscopic effect. Further, a main drug layer and a damp-proofing layer can be uniformly coated on the spherical main drug seed. Further, the thickness of the damp-proofing layer is uniform by the uniform coating of the damp-proofing layer, thereby minimizing the vulnerable surface of the interface surface in contact with moisture and thus having an excellent effect in reducing the absorption of moisture. Further, a coating agent as a damp-proofing agent is uniformly coated on the main drug layer to form the damp-proofing layer, so that a pellet preparation solving the hygroscopic problem of the conventional formulation containing a herbal extract as a main ingredient. [Reference numerals] (AA) Main drug seed; (BB) Main drug layer; (CC) Damp-proofing layer본 발명은 생약 추출엑스를 포함하는 구형의 주약물 씨드, 이를 이용하여 펠렛 제제의 전체 중량 대비 주약의 함량을 증가시키고, 인습성을 개선시킨 생약 추출엑스를 포함하는 펠렛 제제 및 이의 제조방법에 관한 것으로, 본 발명에 따라 제조된 생약 추출엑스 펠렛 제제는 생약 추출엑스를 포함하는 주약물 씨드를 사용함으로써, 펠렛 제제 전체 중량에 대한 주약의 함량을 높이는 효과가 있으므로 환자가 펠렛 제제를 복용할 경우, 1회 복용량을 줄이므로 복용의
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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