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COATING METHOD
专利权人:
Svenn Klüver Jepsen;Gudrun Lasskogen
发明人:
Svenn Klüver Jepsen,Gudrun Lasskogen
申请号:
US13606511
公开号:
US20120328698A1
申请日:
2012.09.07
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention concerns a method for coating granules comprising mesalazine, with a coating mixture comprising two polymers, polymer I and polymer II; said polymer I being selected to allow formation of a closing membrane around said granules in the absence of said polymer II, and said polymer II being selected to act as a water-soluble pore former in said coating mixture; wherein a) the amount of polymer I is adjusted to provide a closing membrane in the absence of polymer II, and b) the amount of polymer II in said coating mixture is adjusted to obtain coated granules which exhibit controlled release of mesalazine. The invention further concerns a product obtainable by the coating method.
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