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METHODE POUR ENDUIRE DES GRANULES CONTENANT DE LA MESALAZINE
专利权人:
FERRING B.V.
发明人:
JEPSEN, SVENN KLUEVER,LASSKOGEN, GUDRUN
申请号:
CA2544572
公开号:
CA2544572C
申请日:
2004.12.16
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention concerns a method for coating granules comprisingmesalazine, with a coating mixture comprising two polymers, polymer I andpolymer II; said polymer I being selected to allow formation of a closingmembrane around said granules in the absence of said polymer II, and saidpolymer II being selected to act as a water-soluble pore former in saidcoating mixture; wherein a) the amount of polymer I is adjusted to provide aclosing membrane in the absence of polymer II, and b) the amount of polymer IIin said coating mixture is ad~justed to obtain coated granules which exhibitcontrolled release of mesalazine. The invention further concerns a productobtainable by the coating method.
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