This invention relates to medical engineering, more particularly, to biocompatible wear resistant nanostructured thin film materials for application as coatings in the fabrication of loadbearing implants, for example, orthopedic and dental prosthetics, dental crowns, implants for maxillofacial surgery, artificial limbs, fixtures etc. Requirements to these materials include high hardness, fatigue resistance, wear and corrosion resistance, biocompatibility and absence of toxicity. The technical result achieved in this invention is providing a multicomponent nanostructured coating (MNC) having high hardness, low elastic modulus, high adhesion to the substrate, low friction coefficient and wear rate, high resistance to long elastic strain to failure and plastic deformation, low surface roughness, negative surface charge in physiological media (4.5 < pH < 9), bioactive surface, biocompatibility and absence of toxicity. Said technical result is achieved as follows. Biocompatible multicomponent nanostructured coatings for load-bearing implants are synthesized on the basis of titanium carbonitride with the addition of elements that improve the mechanical and frictional properties of the coating and provide for its bioactivity, biocompatibility and absence of toxicity. The overall concentrations of the main and additional elements in the coating are in the following relationship (I) where Xi is the overall concentration of the main elements (Ti, C, N) in the coating and Yj is the overall concentration of the additional elements (Ca, Zr, Si, K, Mn, O, P) in the coating. The elemental concentration in the coating is chosen to keep the following component ratios, at.%: Ti : 30 - 50 C : 15 - 40 N : 0.5 - 30 O: 5 - 25 Ca: 0 - 7 Zr: 0 - 20 Si: 0 - 30 P: 0 - 1.5 Mn: 0 - 1.0 K: 0 - 1.0Linvention concerne un agent pour la prévention du glaucome ou pour la prévention ou le traitement de lhypertension oculaire qui présente un effet hypotenseur oculaire puissant pendant une période p
