BESONG, GILBERT,BRAIN, CHRISTOPHER THOMAS,BROOKS, CLINTON A.,CONGREVE, MILES STUART,DAGOSTIN, CLAUDIO,HE, GUO,HOU, YING,HOWARD, STEVEN,LI, YUE,LU, YIPIN,MORTENSON, PAUL,SMITH, TROY,SUNG, MOO JE,WOODHE
申请号:
CA2734802
公开号:
CA2734802C
申请日:
2009.08.20
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The disclosed compounds relate totreatments and therapies for protein kinase-associateddisorders. There is also a need for compounds usefulin the treatment or prevention or amelioration of oneor more symptoms of cancer, transplant rejections,and autoimmune diseases. Furthermore, there is aneed for methods for modulating the activity ofprotein kinases, such as CDK1, CDK2, CDK4, CDK5,CDK6, CDK7, CDK8 and CDK9, using the compoundsprovided herein.