CARBOXAMIDE OR SULFONAMIDE SUBSTITUTED NITROGEN-CONTAINING 5-MEMBERED HETEROCYCLES AS MODULATORS FOR THE ORPHAN NUCLEAR RECEPTOR ROR GAMMA

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专利权人:

PHENEX PHARMACEUTICALS AG

发明人:

GEGE, CHRISTIAN,KINZEL, OLAF,STEENECK, CHRISTOPH,KLEYMANN, GERALD,HOFFMANN, THOMAS

申请号：

SG11201500955R

公开号：

SG11201500955RA

申请日:

2013.05.29

申请国别(地区):

SG

年份:

2015

代理人:

摘要：

The invention provides modulators for the orphan nuclear receptor ROR³ and methods for treating ROR³ mediated diseases by administering these novel ROR³ modulators to a human or a mammal in need thereof. Specifically, the present invention relates to compounds for use ROR³ modulators, wherein the compounds are carboxamide containing cyclic compounds of Formula ( 6 ) to Formula ( 9 ) and the enantiomers, diastereomers, tautomers, N-oxides, solvates and pharmaceutically acceptable salts thereof.

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