Carboxamide or sulfonamide substituted nitrogen-containing 5-membered heterocycles as modulators for the orphan nuclear receptor ror gamma

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专利权人:

PHENEX PHARMACEUTICALS AG

发明人:

KINZEL OLAF,STEENECK CHRISTOPH,GEGE CHRISTIAN,KLEYMANN GERALD,HOFFMANN THOMAS

申请号：

NZ70451213

公开号：

NZ704512A

申请日:

2013.05.29

申请国别(地区):

NZ

年份:

2016

代理人:

摘要：

The invention provides modulators for the orphan nuclear receptor RORy and methods for treating RORy mediated diseases by administering these novel RORy modulators to a human or a mammal in need thereof. Specifically, the present invention provides carboxamide containing cyclic compounds of Formula (1) to Formula (5) and the enantiomers, diastereomers, tautomers, N-oxides, solvates and pharmaceutically acceptable salts thereof.

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