Carboxamide or sulfonamide substituted nitrogen-containing 5-membered heterocycles as modulators for the orphan nuclear receptor ROR gamma

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专利权人:

Phenex Pharmaceuticals AG

发明人:

Gege, Christian,Kinzel, Olaf,Steeneck, Christoph,Kleymann, Gerald,Hoffmann, Thomas

申请号：

AU2013301914

公开号：

AU2013301914B2

申请日:

2013.05.29

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

The invention provides modulators for the orphan nuclear receptor RORy and methods for treating RORy mediated diseases by administering these novel RORy modulators to a human or a mammal in need thereof. Specifically, the present invention provides carboxamide containing cyclic compounds of Formula (1) to Formula (5) and the enantiomers, diastereomers, tautomers, /V-oxides, solvates and pharmaceutically acceptable salts thereof.

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