ISIS INNOVATION LIMITED;GOVERNMENT OF THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
CLARKE, KIERAN,VEECH, RICHARD LEWIS
申请号：
CA2734720
公开号：
CA2734720C
申请日:
2009.04.16
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
A compound which is 3-hydroxybutyl 3-hydroxybutyrate enantiomerically enrichedwith respect to (3R)-hydroxybutyl (3R)-hydroxybutyrate of formula (l): is aneffectiveand palatable precursor to the ketone body (3R)-hydroxybutyrate and maythereforebe used to treat a condition which is caused by, exacerbated by or associatedwithelevated plasma levels of free fatty acids in a human or animal subject, forinstancea condition where weight loss or weight gain is implicated, or to promotealertness orimprove cognitive function, or to treat, prevent or reduce the effects of,neurodegeneration, free radical toxicity, hypoxic conditions or hyperglycaemia.
