Isis Innovation Limited;The United States of America, as represented by the Secretary, Department of Health And Human Services
发明人:
Kieran Clarke,Richard Lewis Veech
申请号：
US14101834
公开号：
US10051880B2
申请日:
2013.12.10
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A compound which is 3-hydroxybutyl 3-hydroxybutyrate enantiomerically enriched with respect to (3R)-hydroxybutyl (3R)-hydroxybutyrate of formula (I) is an effective and palatable precursor to the ketone body (3R)-hydroxybutyrate and may therefore be used to treat a condition which is caused by, exacerbated by or associated with elevated plasma levels of free fatty acids in a human or animal subject, for instance a condition where weight loss or weight gain is implicated, or to promote alertness or improve cognitive function, or to treat, prevent or reduce the effects of neurodegeneration, free radical toxicity, hypoxic conditions or hyperglycaemia.
