Oxford University Innovation Limited;The Govt. Of U.S.A. As Represented By The Secretary Of The Department Of Health And Human Services
发明人:
申请号:
EP09789596.5
公开号:
EP2328858B1
申请日:
2009.04.16
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
A compound which is 3-hydroxybutyl 3-hydroxybutyrate enantiomerically enriched with respect to (3?)»hydroxybutyl (3i?)-hydroxybutyrate of formula (I): is an effective and palatable precursor to the ketone body (3?)-hydroxybutyrate and may therefore be used to treat a condition which is caused by, exacerbated by or associated with elevated plasma levels of free fatty acids in a human or animal subject, for instance a condition where weight loss or weight gain is implicated, or to promote alertness or improve cognitive function, or to treat, prevent or reduce the effects of, neuro degeneration, free radical toxicity, hypoxic conditions or hyperglycaemia.