The present invention relates to compounds of formula I, which is useful in the inhibition of c-Met protein kinase. The invention also provides pharmaceutically acceptable compositions comprising compounds of formula I and methods of using the compositions in the treatment of proliferative disorders.本發明係關於一種含通式I化合物之組合物,其適用於抑制c-Met蛋白激酶。本發明亦提供一種藥學上可接受之含通式I化合物之組合物,及一種使用該組合物治療增生性病症之方法。