Human domain antibodies against components of the human insulin-like growth factor (IGF) system

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专利权人:

发明人:

Dimiter S. Dimitrov,Weizao Chen

申请号：

US14710875

公开号：

US09657096B2

申请日:

2015.05.13

申请国别(地区):

US

年份:

2017

代理人:

摘要：

Antibodies and antibody fragments that bind to insulin-like growth factor (IGF) 1 receptor (IGF-1R) or IGF-2, as well as methods of using the antibodies for inhibiting the IGF-mediated signaling pathway, inhibiting IGF-1R signaling, and treating cancer, are described. A method of detecting the presence of IGF-1R or IGF-2 in a sample using the disclosed antibodies and antibody fragments is also described.

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中国工程科技知识中心

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