THE UNITED STATES OF AMERICA; as represented by THE SECRETARY; DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
Dimitrov, Dimiter S.,Chen, Weizao
申请号：
AU2010303383
公开号：
AU2010303383A1
申请日:
2010.10.07
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The invention provides antibodies or antibody fragments that bind to insulin-like growth factor (IGF) 1 receptor (IGF-1R) or IGF-2, as well as method of using the antibodies for inhibiting the IGF-mediated signaling pathway, inhibiting IGF-1R signaling, and treating cancer. The invention also provides a method of detecting the presence of IGF-1R or IGF-2 in a sample using the inventive antibodies and antibody fragments.
